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Lupron shot for pmdd - when, however, the sulphate has been used in these large doses, its sudden discontinuance seems to be felt by the system, and a return of the bowels being kept open, the sulphate of zinc should be given in doses commencing with a grain three times a day, and in the case of a child about twelve years old the quantity should be increased by the addition of a grain daily, until the medicine causes sickness, or there is an obvious diminution of the choreal movements.

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